Literature
Oxford Gene Technology Expands NGS Offering Into Constitutional Cytogenetics
Oxford Gene Technology recently rolled out its first next-generation sequencing product for constitutional cytogenetics research. The company believes cytogeneticists will adopt its panel to get high-quality single nucleotide variant (SNV) and copy number
Type: Article
CytoSure™ NGS Library Preparation - Instructions for Use
Read and download instructions for use for the CytoSure NGS Library Preparation.
Type: Handbook
Clearance of ctDNA in triple negative and Her2 positive breast cancer patients during neoadjuvant treatment is correlated with pathological complete responses
The primary objective of this study was to assess ctDNA clearance during neoadjuvant treatment as a correlate to effective response to treatment, as benchmarked by clinical complete response (cCR) and pathological complete response (pCR).
Type: Poster
NGS Custom Cancer Panels Overview
Discover the wide range of cancers SureSeq myPanel's pre-optimised NGS custom panel content is available for.
Type: Guide
CytoSure™ Constitutional NGS
Type: Product profile
Interpret NGS Analysis Software – Seamless transition from microarray to NGS in constitutional cytogenetics
At OGT we understand that making the change from microarrays to NGS is a daunting prospect, particularly when it comes to data analysis. This technical note outlines some of the key features we’ve incorporated to help make the change from arrays to NGS as
Type: Application note
SureSeq™ CLL + CNV Panel
Type: Product profile
Assessment of SureSeq™ Interpret software on low-frequency variants using reference standards
Presented at AMP 2019, this poster demonstrates how OGT’s SureSeq Interpret software shows robust and reproducible results in the detection of low-frequency variants using reference standards.
Type: Poster
Concurrent detection of somatic copy number alterations and gene variants (SNV/indels) in CLL samples using a targeted NGS panel
Presented at AMP 2019, this poster demonstrates the capability of SureSeq™ CLL CNV - 14 gene panel to overcome the challenges with detecting copy number alterations currently experienced and provide a possible future single test to be developed for CLL.
Type: Poster
Improving experimental reproducibility through automated hybridisation-based NGS library preparation
In this application note, an Agilent Bravo A Automated Liquid Handling Platform was configured to run the SureSeq NGS library preparation protocol. The results demonstrate marked improvement not only in hands-on-time, but also a number of quality metrics
Type: Application note
SureSeq™ NGS Library Preparation Kit
Type: Product profile
SureSeq Library™ Preparation Handbook
Type: Handbook
SureSeq™ Quick Reference Guide – Good Quality DNA
Type: Guide
SureSeq myPanel™ NGS Custom Cancer Panels
Type: Product profile
Assessment of the performance of a hybridisation-based NGS enrichment panel with as little as 10 ng of severely formalin-compromised DNA
Presented at AMP 2018, this poster illustrates the excellent performance of a hybridisation-based NGS enrichment panel, in conjunction with an FFPE repair mix.
Type: Poster
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