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The impact of microarray probe design on detecting copy number variants at exon-resolution

  • Resource type: App note
  • Application: Haematology, Solid tumour, Cytogenetics & rare disease

CytoSure arrays offer robust copy-number detection with high resolution – detecting CNVs of a few hundred base pairs at the single-exon level. However, a number of different factors need to be taken into account when designing microarrays to make sure that they offer robust performance across the targeted regions. Learn more about the process that we undertake to make sure our arrays perform the best they possibly can.

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The impact of microarray probe design on detecting copy number variants at exon-resolution Image

The use of the InnoScan 710 scanner and Mapix software with CytoSure microarrays

  • Resource type: App note
  • Application: Haematology, Solid tumour, Cytogenetics & rare disease

This application note illustrates the use of the InnoScan 710 scanner and Mapix with a range of OGT CytoSure cytogenetic array formats.

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The use of the InnoScan 710 scanner and Mapix software with CytoSure microarrays Image

Superior detection of chromosomal aberrations using the latest generation of exon-focused constitutional arrays

  • Resource type: White paper
  • Application: Cytogenetics & rare disease

This whitepaper from Dominic McMullan, West Midlands Regional Genetics Laboratory, Birmingham, UK, demonstrates that the CytoSure Constitutional v3 microarray can detect variants not detectable by other microarray platforms.

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Superior detection of chromosomal aberrations using the latest generation of exon-focused constitutional arrays Image

Adoption of the CytoSure Constitutional v3 microarray for increased detection of disease-relevant variants

  • Resource type: White paper
  • Application: Cytogenetics & rare disease

In this white paper, Kris Van Den Bogaert describes how the most current microarray technology is set to increase the detection of disease-relevant variants following a validation and implementation programme at the Department of Human Genetics, University Hospitals Leuven, Belgium.

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Adoption of the CytoSure Constitutional v3 microarray for increased detection of disease-relevant variants Image

Examining the medical exome

  • Resource type: White paper
  • Application: Cytogenetics & rare disease

In this white paper, genetic scientists Dr Tracey Lewis and Dr Emily Farrow discuss how customisable, exon focused array designs complement next generation sequencing (NGS) for clinical genetic research.

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Examining the medical exome Image

Evaluation of DNA labelling kits for enhanced microarray results

  • Resource type: App note
  • Application: Cytogenetics & rare disease

This application note provides a technical evaluation of CytoSure Genomic DNA Labelling Kits compared with another leading DNA labelling kit.

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Evaluation of DNA labelling kits for enhanced microarray results Image

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