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Product summary

  • Technology Arrays
  • Product No. 020020 (24 reactions)
    500040 (96 reactions)
  • Intended use For Research Use Only; Not for Diagnostic Procedures.

Overview

The labelling of DNA samples used in array comparative genomic hybridisation (aCGH) is a critical step in the experimental process as poor labelling can result in inaccurate data. OGT’s CytoSure® Genomic DNA Labelling Kits have been uniquely developed and optimised to enable rapid delivery of high quality results with high signal-to-noise ratios.

CytoSure Genomic DNA Labelling Kit delivers:

  • Optimised formats to suit your throughput requirements
  • Reliable high quality results through higher signal intensity
  • Fast and simple procedure
  • Everything you need, from reagents to plasticware

Capabilities

Optimised formats to suit your throughput requirements

CytoSure Genomic DNA Labelling Kits are available in 2 formats to suit your throughput requirements. The CytoSure Genomic DNA Labelling Kit enables labelling of 24 samples and is ideal for labs running one or two arrays a week. The CytoSure HT Genomic DNA Labelling Kit is designed specifically for high-throughput labs and allows simultaneous labelling of 96 samples. This plate-based format offers faster sample processing, a lower cost per sample and decreased sample-to-sample variation using a master mix format. It is also easier to automate and track samples.

Reliable high quality results

CytoSure Genomic DNA Labelling Kits have been rigorously tested with a wide range of sample types to ensure optimal performance. The unique formulation ensures superior signal-to-noise ratios allowing confident detection of copy number variation (Figure 1). This high signal-to-noise ratio means that even small aberrations can be reliably detected (Figure 2).

Fast and simple procedure

CytoSure Genomic DNA Labelling Kits offer much faster DNA labelling and clean up than traditional enzymatic labelling procedures. Labelling reactions using both the 24 and 96 reaction kits can easily be completed in a single day (Figure 3). The procedure can also be automated for implementation in high-throughput workflows.

Everything you need, from reagents to plasticware

OGT offers the complete labelling solution — protocols, reagents, clean-up plates or columns and collection tubes. The unique kit formulation has been optimised for use with CytoSure arrays, which offer a wide variety of content and formats to suit your specific requirements. CytoSure arrays utilise 60-mer oligonucleotide probes, which are proven to offer higher signal-to-noise ratios and increased sensitivity and specificity1.

CytoSure products provide a complete and integrated solution for cytogenetics research in your lab — from DNA labelling and arrays to analysis software and full workflow automation.

CytoSure Constitutional v3 and Constitutional v3 +LOH Arrays workflow

Labelling Image

Labelling

  • CytoSure Genomic DNA Labelling Kits
  • CytoSure Sample Tracking Spike-ins
Scanning Image

Scanning

  • Agilent C or SureScan
  • Innopsys Innoscan 710 & 900
  • Axon / Molecular devices GenePix 4300 & 4400
  • NimbleGen MS200 / Tecan Power Scanner

What our customers say

References

  1. Curtis, C. et al (2009) The pitfalls of platform comparison: DNA copy number array technologies assessed. BMC Genomics 10, 588-610

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