Integrated technologies for accurate mutation detection

Various technologies are available to study the mutations that cause cancer, but none are capable of accurate detection of all types of genetic aberrations. By combining information from multiple technologies, researchers can analyse complex cancer samples and get the most complete overview of disease-driving mutations.

OGT offers an integrated portfolio of products providing clinical researchers with the most advanced tools available to study solid tumors, including CytoCell® fluorescence in-situ hybridization (FISH) probes and myProbes® custom FISH probes, SureSeq™ Next Generation Sequencing (NGS) panels and myPanel™ custom panels, and CytoSure® array products and custom arrays. We partner with leading clinical researchers to advance discoveries by providing proven, high-quality solutions.

Featured solid tumor products

FISH probes

CytoCell CDKN2A Probe Gold Image

CytoCell CDKN2A Probe Gold

The CDKN2A Probe covers CDKN2A (P16) gene and flanking regions, and is labeled in gold.

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CytoCell FGFR1 Breakapart/ Amplification Image

CytoCell FGFR1 Breakapart/ Amplification

The FGFR1 Breakapart/Amplification probe consists of a green 272kb probe and a red 267kb probe, which are positioned on each side of the FGFR1 gene. The 8-centromere probe in blue acts as a control for chromosome 8.

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NGS panels

SureSeq Germline Breast Cancer + CNV Panel Image

SureSeq Germline Breast Cancer + CNV Panel

The SureSeq Germline Breast Cancer + CNV Panel has been developed to provide comprehensive coverage of 7 key genes implicated in breast and ovarian cancer, including BRCA1 and BRCA2. Detecting SNVs and indels, as well as exon-level to whole gene CNVs, provides researchers with a single NGS workflow to study clinically relevant aberrations and alleviates the burden of running multiple assays. The figure (above) illustrates the excellent coverage uniformity across BRCA1 exons 9, 10 and 11 [A] and BRCA2 exons 9, 10 and 11 [B].

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SureSeq myPanel NGS Custom Colorectal Cancer Panel Image

SureSeq myPanel NGS Custom Colorectal Cancer Panel

Choose your perfect colorectal NGS panel from our range of fully tested and optimized panel content. Simply mix and match the genes or individual exons you require and get the most out of your sequencing runs. The figure (above) illustrates the excellent uniformity of coverage of BRAF exon 15 (top) and TP53 exons 3 - 9 (bottom).

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Featured solid tumor resources

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