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Next-generation sequencing: The future of chronic lymphocytic leukemia (CLL) genomics?

28 Nov 2024

Discover how next-generation sequencing is reshaping CLL prognosis, streamlining the process and offering more comprehensive insights than ever before.

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Future Of CLL Featured

Next-generation sequencing: The future of chronic lymphocytic leukemia (CLL) genomics?

28 Nov 2024

Discover how next-generation sequencing is reshaping CLL prognosis, streamlining the process and offering more comprehensive insights than ever before.

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Sequencing Depth Vs VAF Featured

Next-generation sequencing: Sequencing depth vs. VAF sensitivity

05 Nov 2024

Gain an understanding of the relationship between sequencing depth and Variant Allele Frequency (VAF) sensitivity, which plays a significant role in accurately detecting genetic variants, especially in Measurable Residual Disease (MRD) detection.

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Simple Fixes For Reducing High Background Signal Featured V2

How do I reduce high background in my FISH assay?

04 Oct 2024

Learn how to combat high background fluorescence in your FISH assays with inside tips on sample preparation, hybridization conditions and more.

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Partnering with OGT: Empowering the establishment of a FISH laboratory in Nigeria

21 Jun 2024

At OGT we are proud of the collaborations we have with labs all over the world. In this blog discover how Norah O. Akinola, Professor of Haematology at the Obafemi Awolowo University in Nigeria, worked with OGT experts to establish a FISH laboratory by upgrading their existing cytogenetics facility.

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Image Showing DNA Fusion Featured

Detecting fusion events in AML with NGS

29 May 2024

We explore the guidelines and the different methods for fusion event detection, including the potential of RNA-based NGS to help pave the way for personalized therapies and improved patient outcomes.

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Celebrating the women of OGT

14 Feb 2024

Today we celebrate International Day of Women and Girls in Science. Our OGT family includes many women having successful STEM careers. Take a look at some of their stories across various roles in the OGT organization...

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OGTs insights from ASH 2023 Part 2 - Multiple Myeloma

OGT’s insights from ASH 2023: Part 2 – Old biomarkers, new tricks

22 Jan 2024

In the second part of our latest blog series - “Old biomarkers, new tricks" - we highlight the ongoing efforts to bring BCL-2 inhibitors to the forefront in t(11:14) translocation cases of multiple myeloma, and how FISH probes can support clinical investigations.

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OGTs insights from ASH 2023 - Part 1 AML

OGT’s insights from ASH 2023: Part 1 – Old biomarkers, new tricks

09 Jan 2024

Didn’t get a chance to talk to us at ASH 2023? Read the first part of our latest blog series, which describes the potential of menin inhibitors for acute leukemia, including the use of IVDR approved FISH probes in clinical trials.

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Insights on IVD regulation: An interview with Steve Chatters

22 Nov 2023

In March 2023, we became the very first manufacturer of FISH probes to be granted IVDR certification. In our latest blog we speak with Steve Chatters, Executive Vice President of Regulatory, Medical and Quality Affairs, about OGT's long-standing expertise in healthcare regulation, and the journey towards IVDR certification.

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Driving FISH Progress By Working In Partnership With Our Customers Featured Image

Driving FISH progress by working in partnership with our customers

14 Sep 2023

We sit down with two of our Field Application Scientists, Ashley Hart and Jenny Morse, to discuss the technical expertise they offer to OGT customers all over North America. And we chat with one of our customers, Kathleen Kretkowski, about a real-life example of OGT support in action.

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Myeloid Malignancies’ Driver Mutations KMT2A, A Gene For Epigenetic Regulation Featured Image

Myeloid malignancies’ driver mutations - Part #2: KMT2A, a gene for epigenetic regulation

05 Jun 2023

Myeloid malignancies are a group of diseases with wide heterogeneity. In this blog, we will explore the KMT2A gene, previously known as the MLL gene, and its influence upon myeloid malignancies.

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Is NGS set to become the new gold standard in constitutional genetics?

Constitutional genetics: is NGS driving a transformation?

10 May 2023

Is NGS set to become the new gold standard in constitutional genetics? Discover how NGS offers greater insight into indels, CNVs, LOH, mosaicism and more.

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