CytoSure™ Custom Designed aCGH Arrays
Focused custom aCGH arrays designed by the microarray experts.
CytoSure Custom arrays allow you to benefit from OGT’s extensive array design expertise to produce an array matching your precise specifications. These arrays are ideal if you want to know the precise coordinates of an aberration by analysing specific areas of the genome at high resolution.
CytoSure Custom arrays deliver:
- Complete confidence in the design of your array
- Flexible array content and format
- Fast and easy data interpretation
Complete confidence in the design of your array
OGT have designed hundreds of custom arrays for some of the world’s leading researchers. All probes are in-silico optimised and optional empirical validation of the array content ensures optimal performance. In addition you are able to view the selected probes using our unique Oligome™ viewer software prior to fabrication so that any suggested adjustments or alterations can be implemented.
Flexible array content and format
CytoSure Custom arrays can be designed against any fully or partially sequenced genome as well as against sequencing data. The array content is selected from OGT’s proprietary Oligome™ database — a database of more than 23 million oligonucleotide probes designed to the latest release of the human genome. In addition, OGT has extensively research-validated SNP content for detection of uniparental disomy, which can be incorporated into the array design. CytoSure Custom arrays can be designed in a variety of formats depending on your desired level of focus, with 1, 2, 4, or 8 arrays available per slide to provide the most cost-effective solution for your research (Figure 1). Processing can be undertaken in your lab or in OGT’s state-of-the art high-throughput laboratory in Oxford, UK.
Figure 1: Multiple arrays on a single slide can reduce costs and improve consistency. Depending on your desired level of focus you can design 1, 2, 4, or 8 arrays per slide for maximum flexibility.
Fast and easy data generation
Our complimentary CytoSure Interpret Software, which accompanies all CytoSure arrays, is a powerful, easy-to-use package for the analysis of copy number variation (CNV) (Figure 2). Innovative features such as the Accelerate Workflow enable the automation of data analysis workflows, minimising the need for user intervention and maximising the consistency and speed of data interpretation. CytoSure Interpret Software also includes extensive annotation tracks covering syndromes, genes, exons, CNVs and recombination hotspots — each of which link to publicly available databases such as Decipher and the Database of Genomic Variants providing results in context.
Figure 2: Automated aberration detection with CytoSure analysis software, showing clear detection of chromosomal abnormalities.
Contact us to discuss your custom array design project.
|CytoSure Custom Array||Microarray with a choice of formats; CytoSure Interpret software||Enquire||Get a quote|
|CytoSure Genomic DNA Labelling Kit||24 reactions: clean-up columns, dyes, nucleotide mix, random primers, enzyme, collection tubes||020022||Get a quote|
|CytoSure HT Genomic DNA Labelling Kit||96 reactions: 2 purification plates, nucleotide mix, random primers, enzyme, collection tubes||500040||Get a quote|
CytoSure™ products are for research use only; not for use in diagnostic procedures.
Evaluating and implementing CytoSure™ microarrays
In this white paper, Kath Smith, Consultant Clinical Scientist at Sheffield Children’s NHS Foundation Trust discusses her laboratory’s experience of transitioning to OGT CytoSure arrays.
CytoSure™ Array Handbook (4x44k and 4x180k formats)
CytoSure™ Array Handbook (8x15k and 8x60k formats)
CytoSure™ HT Array Handbook (8x15k and 8x60k formats)
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