CytoSure™ Custom Designed aCGH Arrays
Focused custom aCGH arrays designed by the microarray experts.
CytoSure Custom arrays allow you to benefit from OGT’s extensive array design expertise to produce an array matching your precise specifications. These arrays are ideal if you want to know the precise coordinates of an aberration by analysing specific areas of the genome at high resolution.
CytoSure Custom arrays deliver:
- Complete confidence in the design of your array
- Flexible array content and format
- Fast and easy data interpretation
Complete confidence in the design of your array
OGT have designed hundreds of custom arrays for some of the world’s leading researchers. All probes are in-silico optimised and optional empirical validation of the array content ensures optimal performance. In addition you are able to view the selected probes using our unique Oligome™ viewer software prior to fabrication so that any suggested adjustments or alterations can be implemented.
Flexible array content and format
CytoSure Custom arrays can be designed against any fully or partially sequenced genome as well as against sequencing data. The array content is selected from OGT’s proprietary Oligome™ database — a database of more than 23 million oligonucleotide probes designed to the latest release of the human genome. In addition, OGT has extensively research-validated SNP content for detection of uniparental disomy, which can be incorporated into the array design. CytoSure Custom arrays can be designed in a variety of formats depending on your desired level of focus, with 1, 2, 4, or 8 arrays available per slide to provide the most cost-effective solution for your research (Figure 1). Processing can be undertaken in your lab or in OGT’s state-of-the art high-throughput laboratory in Oxford, UK.
Figure 1: Multiple arrays on a single slide can reduce costs and improve consistency. Depending on your desired level of focus you can design 1, 2, 4, or 8 arrays per slide for maximum flexibility.
Fast and easy data generation
Our complimentary CytoSure Interpret Software, which accompanies all CytoSure arrays, is a powerful, easy-to-use package for the analysis of copy number variation (CNV) (Figure 2). Innovative features such as the Accelerate Workflow enable the automation of data analysis workflows, minimising the need for user intervention and maximising the consistency and speed of data interpretation. CytoSure Interpret Software also includes extensive annotation tracks covering syndromes, genes, exons, CNVs and recombination hotspots — each of which link to publicly available databases such as Decipher and the Database of Genomic Variants providing results in context.
Figure 2: Automated aberration detection with CytoSure analysis software, showing clear detection of chromosomal abnormalities.
Contact us to discuss your custom array design project.
|CytoSure Custom Array||Microarray with a choice of formats; CytoSure Interpret software||Enquire||Get a quote|
|CytoSure Genomic DNA Labelling Kit||24 reactions: clean-up columns, dyes, nucleotide mix, random primers, enzyme, collection tubes||020022||Get a quote|
|CytoSure HT Genomic DNA Labelling Kit||96 reactions: 2 purification plates, nucleotide mix, random primers, enzyme, collection tubes||500040||Get a quote|
CytoSure™ products are for research use only; not for use in diagnostic procedures.
Evaluation of DNA labelling kits for enhanced microarray results
This application note provides a technical evaluation of CytoSure™ Genomic DNA Labelling Kits compared with another leading DNA labelling kit.
The impact of microarray probe design on detecting copy number variants at exon-resolution
Different factors need to be taken into account when designing microarrays to make sure that they offer robust performance across the targeted regions. Learn more about the process we undertake to make sure our arrays perform the best they possibly can.
The use of the InnoScan® 710 scanner and Mapix® software with CytoSure™ microarrays
This application note illustrates the use of the InnoScan 710 scanner and Mapix with a range of OGT CytoSure cytogenetic array formats.
An integrated approach to profiling haematological disorders
For accurate detection of all types of genetic aberrations, various technologies are used. View OGT's integrated portfolio of products that allow the accurate analysis of haematological disorders.
An integrated approach to tumour profiling
Various technologies are available to study the mutations that cause cancer, but none is capable of accurate detection of all types of genetic aberrations. View OGT's integrated portfolio of products that allow the accurate analysis of solid tumours.
Integrated solutions for the genomic study of inherited disease
Our class-leading products are designed for the robust identification of the whole range of genomic variation, with an emphasis on custom solutions to target the regions important for your research.
Evaluating and implementing CytoSure™ microarrays
In this white paper, Kath Smith, Consultant Clinical Scientist at Sheffield Children’s NHS Foundation Trust discusses her laboratory’s experience of transitioning to OGT CytoSure arrays.
Basics of array comparative genomic hybridisation (aCGH)
This poster illustrates the basics of how aCGH works and some of the applications in which it is used.
What’s wrong with my arrays?
Wet-lab processing is key to achieving the highest quality array data – find the solution to improve your data quality with our poster.