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Fluorescence in situ hybridisation (FISH) is a cytogenetic technique that can detect specific sites of DNA sequences in metaphase or interphase cells.

 

Chromosomal aberrations detected by FISH

In this video learn more about the different chromosomal aberrations detected by FISH.

 

Examples of common FISH signal patterns

View common deletion, breakapart, amplification and translocation signal patterns.

Deletion probes:

Deletion probes

 

Dual-colour breakapart probes:

Dual-colour breakapart probes

 

Deletion/fusion probes:

Deletion/fusion probes

 

Tri-colour breakapart probes:

Tri-colour breakapart probes

 

Amplification probes:

Amplification probes

 

Translocation, dual fusion probes:

Translocation, dual fusion probes

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