Figure 1: Characteristic banding pattern produced by exposure to trypsin during G banding. G band light regions tend to be gene rich. G band dark regions tend to be gene poor. Giemsa banding is a technique used in cytogenetics to produce a visible karyotype by staining condensed chromosomes.
Figure 2. Metacentric (left), submetacentric (centre) and acrocentric (right) chromosomes.
Gene names have been updated to reflect current HUGO Gene Nomenclature Committee (HGNC) approved symbols. Where this affects existing product names, the approved HGNC symbol is placed into brackets. All gene names were checked and updated according to the HGNC database1 as of April 2019.