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Product summary

  • Technology FISH
  • Application Cytogenetics & rare disease
  • Areas of interest Constitutional
  • Region Xp11.1-q11.1
    Yp11.1-q11.1
    Yq12
  • Label    
  • Product Code LPE 0XYc (10 tests)
    LPE 0XYq (10 tests)
  • Regulatory Status In vitro diagnostic. This product is intended to be used on Carnoy’s solution (3:1 methanol/acetic acid) fixed haematological samples. Disease information supported by the literature and is not a reflection of the intended purpose of this product.

Overview

Probe specification

Chromosome X α-satellite (DXZ1) and Chromosome Y α-satellite (DYZ3)

  • DXZ1, Xp11.1- q11.1, Green
  • DYZ3, Yp11.1- q11.1, Red

This enumeration probe set contains chromosome specific alphoid DNA repeat sequences located at the centromeres of chromosome X and chromosome Y.

Chromosome X α-satellite (DXZ1) and Chromosome Y satellite III (DYZ1)

  • DXZ1, Xp11.1- q11.1, Green
  • DYZ1, Yq12, Red

This enumeration probe set contains chromosome specific DNA repeat sequences located at the centromere of chromosome X and in the heterochromatic block of chromosome Y.

 

Probe information

OGT's CytoCell® satellite probes are specific for human chromosomes. They are highly repeated human DNA sequences found in the centromere, pericentromeric or heterochromatic block of each of the 24 chromosomes. The probes enable the identification and enumeration of human chromosomes in interphase cells or metaphase chromosomes from peripheral blood samples.

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