SureSeq myPanel™ NGS Custom Cancer Panels

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A regularly updated, expert-curated library of pre-optimised cancer panel content for you to select from. Simply mix and match the gene, exonic or intronic content you need to create an NGS cancer panel that meets your exact requirements.

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For more information about any OGT product or service, please contact us.

Overview

SureSeq myPanel offers:

  • Hybridisation-based panel delivering unparalleled coverage uniformity — detect low-frequency variants consistently with confidence and minimise the requirement for supplementary fill-in with Sanger sequencing
  • Pre-optimised panels that meet your technical requirements and work with your samples (including FFPE tissue) — no more laborious in-house optimisation, decreasing assay development time
  • Bespoke panel content — sequence only what’s relevant for your cancer research, increase throughput and save on sequencing reagents
  • Panel content designed with experts and from current literature to target all relevant regions including intronic and splice sites — get the most comprehensive insight into disease-driving mutations

Getting started with your next SureSeq myPanel Custom Cancer Panel could not be simpler...

Let us know your cancer(s) of interest and allow Oxford Gene Technology to put our expertise to work in advancing your cancer research.

Design your panel now

Ordering Information

Product Contents Cat. No. Price
SureSeq myPanel NGS Custom Cancer Panels Enrichment baits; SureSeq Interpret Software various Get a quote

 

SureSeq: For research use only; not for use in diagnostic procedures.

Details

Tired of paying to sequence genes you’re not interested in? Then don’t!

Simply select the gene, exonic or intronic content you need from Oxford Gene Technology’s (OGT) regularly updated, expert-curated library of pre-optimised cancer panel content. Our unique panel design coupled with hybridisation-based enrichment offers unparalleled coverage completeness and uniformity. This allows the accurate detection of difficult to sequence, low-frequency variants and minimises the requirement for supplementary fill-in with Sanger sequencing.

Design your panel now

myPanel — Excellent coverage of “difficult” genes

CEBPA gene

Figure 1: Accurate detection of difficult to sequence genes. Mutations in the CEBPA gene are among the most common molecular alterations in AML and bear important significance. Sequencing of the CEBPA gene is often hampered by a repetitive nucleotide sequence and a high GC-rich content, which can lead to technical challenges in assay design, requiring a supplementary fill-in with Sanger sequencing. OGT’s expert bait design overcomes these issues, offer a high level of uniformity coverage for a notoriously difficult gene to sequence. 

myPanel — Don’t miss critical variants

CALR gene

Figure 2: Sensitive detection of critical variants. The CALR gene is commonly mutated in various myeloproliferative neoplasms (MPNs). It is critical to identify key CALR indels (types 1 and 2 causing a frameshift) as well as increasingly recognised point mutations in this gene. OGT’s expert bait design offers excellent coverage uniformity across low-complexity regions with low nucleotide diversity (such as CALR exon 9), compared to other commercially available bait designs, which suffer from a considerable dip in coverage.

myPanel — Customise the following panels:

Solid Tumour PanelsGene List
Breast cancer View gene list
Colorectal View gene list
Glioma View gene list
Lung Cancer View gene list
Ovarian Cancer View gene list
Melanoma View gene list
Prostate Cancer View gene list
Sarcoma View gene list

 

Haematology PanelsGene List
AML View gene list
CLL View gene list
CML View gene list
Core MPN View gene list
MPN/MDS overlap View gene list
Myeloid View gene list

View a complete list of currently available genes. 

Can't see a panel that exactly meets your requirements, let us know the genes you are interested in and we'll create it.

We were delighted with the performance of the SureSeq panel. It showed complete concordance with our other techniques, detecting all known mutations with excellent sensitivity down to 1% [MAF (minor allele frequency)], including, in one case, a JAK2 V617F mutation which was not detected by ddPCR due to a second mutation under the primer. The panel also demonstrated mutations in other genes in samples with low level JAK2 V617F and good correlation between allele frequencies and quantitative analysis by ddPCR. We are planning to adopt the panel in the near future." Dr Anna Skowronska, R&D Scientist, Haemato-Oncology team, West Midlands Regional Genetics  Laboratory (WMRGL) of the Birmingham Women’s NHS Foundation Trust, UK

Getting started with your next SureSeq myPanel Custom Cancer Panel could not be simpler...

SureSeq myPanel

Let us know your cancer(s) of interest and allow OGT to put our expertise to work in advancing your cancer research.

Design your panel now

Ordering Information

Product Contents Cat. No. Price
SureSeq myPanel NGS Custom Cancer Panels Enrichment baits; SureSeq Interpret Software various Get a quote
SureSeq Myeloid Panel (16 reactions) Enrichment baits sufficient for 16 samples; SureSeq Interpret Software 600075 Get a quote
SureSeq Myeloid Panel (96 reactions) Enrichment baits sufficient for 96 samples; SureSeq Interpret Software 600076 Get a quote
SureSeq Ovarian Cancer Panel (96 reactions) Enrichment baits sufficient for 96 samples; SureSeq Interpret Software 600074 Get a quote
SureSeq Ovarian Cancer Panel (16 reactions) Enrichment baits sufficient for 16 samples; SureSeq Interpret Software 600073 Get a quote
Sure Seq FFPE DNA Repair Mix (16 reactions) Enzyme mix and buffer sufficient for 16 FFPE DNA samples 500079 Get a quote
SureSeq NGS Library Preparation Kit (16)  Bundle of 1 x library preparation kit (16) containing adaptors, PCR primers and enzymes sufficient for 16 samples and 1 x SureSeq NGS Index Kit – Collection A 500070 Get a quote
SureSeq NGS Library Preparation Kit (48)  Bundle of 3 x library preparation kit (16), containing adaptors, PCR primers and enzymes sufficient for 48 samples and 1 x SureSeq NGS Index Kit – Collection B 500073 Get a quote
SureSeq NGS Index Kit - Collection A (16) 16 different indexes, each sufficient for 4 samples [included with SureSeq NGS Library Preparation Kit (16)] 500071
Get a quote
SureSeq NGS Index Kit - Collection B (48) 48 different indexes, each sufficient for 4 samples [included with SureSeq NGS Library Preparation Kit (48)] 500072 Get a quote

Find out more about the SureSeq Myeloid PanelSureSeq Ovarian Cancer Panel and the SureSeq NGS Library Preparation Kit

SureSeq: For research use only; not for use in diagnostic procedures.