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Welcome to the latest edition of DNA Dispatch, the quarterly newsletter from OGT, your hybridization experts.

Don’t miss key genomic insights in your Myeloid MRD assays

This highly-targeted panel incorporates gene content driven by leading cancer expert recommendations, while keeping DNA input and sequencing requirements low.

Transform your myeloid MRD approach:

  • Discover more variants with ultra-low detection as low as 0.01% VAF
  • Interrogate challenging biomarkers, including large FLT3-ITDs
  • Easily visualize changes in longitudinal MRD sample studies
Don’t miss key genomic insights in your Myeloid MRD assays Image

30 years of impact, innovation and partnership! Image

30 years of impact, innovation and partnership!

Since 1995, OGT has grown, evolved and built enduring partnerships.

This milestone reflects our team’s dedication, innovation and passion that has made three decades of excellence possible, and above all, the trust and support of our loyal customers through every chapter of our story.

New white paper

Deploying a custom NGS panel for combined myeloid and lymphoid neoplasm analysis

To address challenges of multiple sequential tests, increasing cost, complexity and turnaround time, Kingston Health Sciences Centre collaborated with OGT to develop a custom SureSeq myPanel™, designed to detect SNVs, indels, ITDs, PTDs and CNVs at both exon and whole-gene levels.

Deploying a custom NGS panel for combined myeloid and lymphoid neoplasm analysis Image

Illuminating genomes across the globe with CytoCell FISH probes Image

Illuminating genomes across the globe with CytoCell FISH probes

Used in laboratories worldwide, CytoCell® FISH probes empower cytogenetic teams with precision, clarity and confidence.

Discover how our CytoCell probes were utilized in recent cytogenetics studies*:

  • Study 1: "Structural variants dysregulating FOXC2 cause lymphoedema distichiasis syndrome: A series of case reports"
  • Study 2: "Chromoanagenesis in haematological malignancy: Review of samples from patients with acute leukemia and MDS"

How do I resolve black holes on the array during aCGH?

Using too little hybridization solution can leave areas of the array insufficiently covered, leading to local drying and the appearance of black holes in the aCGH signal.

This can be resolved by ensuring the correct volume of hybridization solution has been used and that no leakage of hybridization solution has occurred.

How do I resolve black holes on the array during aCGH? Image

How does NGS-based MRD detection stack up against existing technologies? Image

How does NGS-based MRD detection stack up against existing technologies?

NGS-based MRD assessment is helping labs to capture a wide assortment of MRD markers in AML samples and when combined with optimized bioinformatic analysis, unlocks their ability to—at scale—identify and assess variants that impact disease course and/or therapeutic response.

View and download our infographic to learn more about why NGS has been adopted as a more expansive genomic technology for AML MRD

Don’t forget…Our FAS team can be contacted online with free support advice

 

* Providing links to these publications is intended for educational purposes only and does not replace independent professional judgement. OGT does not endorse or approve, and assumes no responsibility for, the content, accuracy or completeness of the information presented in these publications.