SureSeq myPanel Myeloid Fusion MRD NGS Panel

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Overview

Many MRD workflows focus on SNVs, indels or ITDs, leaving fusion tracking handled through separate qPCR, FISH or single-target methods. The SureSeq myPanel™ Myeloid Fusion MRD Panel adds fusion detection to an NGS workflow to help reduce fragmentation and support longitudinal MRD assessment. Focused content, compatible with the SureSeq™ Myeloid MRD Plus NGS Panel and Interpret NGS Analysis Software workflows, enables the longitudinal visualization you need for MRD analysis.

Detect lower-level fusions

Identify clinically relevant RNA fusions at MRD-level sensitivity for earlier signal capture in AML samples

Simplify longitudinal assessment

Reduce reliance on separate qPCR/FISH and NGS assays by bringing fusion MRD into a streamlined NGS workflow

Fill the fusion MRD gap

Add fusion tracking to existing MRD workflows where many current NGS panels are focused on SNVs, indels and ITDs

Identify MECOM gene expression changes

Confidently quantify MECOM expression levels and identify MECOM-associated events so you have the most informative profile for your AML samples

Product performance

MECOM relative expression

Figure 1 (right) shows relative expression of MECOM in HNT34 cells (n=2 replicates per dilution) as compared to housekeeping genes (TFRC, AAAS and C10orf88).