The application of a hybridisation-based next-generation sequencing (NGS) enrichment panel for the analysis of key genes involved in ovarian and breast tumours using DNA from FFPE samples
The use of the InnoScan® 710 scanner and Mapix® software with CytoSure™ microarrays
This application note illustrates the use of the InnoScan 710 scanner and Mapix with a range of OGT CytoSure cytogenetic array formats.
Type: Application note
Q&A with Dr. Theresa C. Brown, Tulane University School of Medicine.
Choosing the best enrichment assay
The application of a hybridisation-based NGS enrichment panel for the analysis of somatic variants in tumour samples and reference standards
Presented at AGT 2017, this poster outlines the application of a hybridisation-based NGS enrichment panel for the analysis of solid tumour somatic variants, demonstrating 100% concordance in variant detection in both genomic and formalin-compromised DNA.
The application of a one-day hybridisation-based enrichment protocol for NGS incorporating a rapid (30 minute) hybridisation step
Presented at AGT 2017, this poster outlines how OGT has optimised a one-day hybridisation-based enrichment protocol for NGS incorporating a rapid 30 hybridisation step.
CytoSure Interpret Software – User Guide
CytoSure™ Interpret Software Update Guide
An approach for determination of copy number variation using short-read next-generation sequencing
Presented at ESHG 2017, this poster outlines how OGT’s combined bioinformatics and focused panel approach offers the ability to analyse both germline copy number variation (CNV) and single nucleotide variation (SNV) using a single assay.
SureSeq myPanel™ Laboratory Programme
Type: Lab Programme
Integrated solutions for the genomic study of inherited disease
Our class-leading products are designed for the robust identification of the whole range of genomic variation, with an emphasis on custom solutions to target the regions important for your research.
SureSeq myPanel™ NGS Custom Breast Cancer panel
Type: Product profile
Understanding myeloid disorders with next-generation sequencing
This white paper describes how OGT’s SureSeq™ Myeloid Panel helps researchers identify and decipher the complex genetic origins of myeloproliferative disorders.
Type: White paper
Optimised, 1-day hybridisation-based NGS protocol yields 1% variant detection in MPN samples, as quickly and cost-effectively as multiplex PCR
Presented at AMP 2016, this poster outlines how the SureSeq™ Core MPN Panel can accurately detect alleles down to 1% variant allele fraction (VAF) in JAK2 (V617F) at a read depth of >1000x, facilitating reliable detection.
The use of a hybridisation-based NGS enrichment panel for the confident identification of a broad range of low frequency variants from as little as 50ng of challenging clinical research FFPE samples
Presented at AMP 2016, this poster outlines how the SureSeq FFPE DNA Repair Mix significantly improves NGS library yields, with an increase of mean target coverage (increased by >2.2 fold), resulting in more meaningful data.