Assessment of SureSeq™ Interpret software on low-frequency variants using reference standards
James Reid, Venu Pullabhatla, Laura Parkes, John Shovelton, Ezam Uddin, Lyudmila Georgieva, Aysel Heckel, Jolyon Holdstock, Graham Speight
Presented at AMP 2019, this poster demonstrates how OGT’s SureSeq Interpret software shows robust and reproducible results in the detection of low-frequency variants using reference standards.
Next-Generation Sequencing (NGS) has enabled large-scale identification of variants with increased reliability and accuracy. This is crucial for detecting low-frequency variants for cancer research.
At Oxford Gene Technology (OGT), we have developed SureSeq Interpret, as a partner software tool to our SureSeq NGS panels, to facilitate data analysis in an easy, user-friendly way. SureSeq Interpret has been benchmarked with known and validated variants from control reference standards achieving high concordance.
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