Molecular Genetics eNews

February 2019 edition

We’d like to share an update we’ve made to our custom NGS panels offering which is now available with SureSample™ giving you a set of single nucleotide polymorphisms (SNPs) to add to your custom NGS panel; helping you in your sample identification - read on and find out more.

You’ll also find some handy hints and tips for using our CytoSure™ Interpret Software in our ever-popular video series developed by our technical specialist, Peter Gray.

Kind regards,

Aysel Heckel, VP Sales and Support, Americas

Aysel Heckel

 

 

 

 

 

SureSeq myPanel™ NGS Custom Cancer panels, now with SureSample

SureSeq myPanel NGS Custom Cancer panels, now with SureSampleThe unique design of OGT’s SureSeq myPanel NGS Custom Cancer panel content coupled with hybridisation-based enrichment offers unparalleled coverage completeness and uniformity.

OGT now offers SureSample, a set of 44 single nucleotide polymorphisms (SNPs) to add to your custom NGS panel to assist in sample identification.

Throughout the library preparation process, SureSample provides reliable sample tracking and easy identification of sample mix-up. Just add SureSample to your next custom NGS panel design.

Find out more >

 

CytoSure Interpret Software Tutorial Series – Automatic classification of Aberrations

CytoSure Interpret Software Tutorial Series – Automatic classification of AberrationsIn the latest of our popular CytoSure Interpret Software Tutorial Series, Peter Gray, OGT Field Application Specialist - NGS and Arrays, reviews the automatic CNV classification feature.

Pete covers how to set up and customise classifier sets, illustrates how they can aid the interpretation process and provide a faster, more standardised analytical workflow. 

Watch the video >

 

 

 

Blog - Don’t Amplify the Noise

Blog - Don’t Amplify the NoiseIn our new Blog, Dave Cook, Senior Manager, Regional Marketing at OGT compares the pros and cons of amplicon-based and hybridisation-based sequencing strategies.

He illustrates how the latter approach overcomes many of the issues of the former, especially with respect to the difficulty of assessing the true complexity of the library and ensuring good coverage uniformity.

Read the blog >

 

 

 

Beyond FISH, SNVs and indels – improved resolution of translocation detection using NGS

Poster: Beyond FISH, SNVs and indels – improved resolution of translocation detection using NGS

Presented at AMP 2018, this poster demonstrates how the superior uniformity of coverage of the hybridisation-based approach of the SureSeq protocol in combination with a SureSeq myPanel NGS Custom panel reliably detects somatic BCR-ABL1 translocations with different breakpoint locations down to a 5% frequency. 

View the poster >

 

 

 

 

 

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