The TEL (ETV6) probe mix, labeled in red, contains a probe covering a 180kb region between the markers D12S845 and D12S89 and a second probe centromeric to the ETV6 gene, extending 168kb from the marker D12S1898. For RUNX1, there are two probes, labeled in green, one covering a 156kb region centromeric to the RUNX1 gene, including the CLIC6 gene and a second probe covering a 169kb region, including the markers D21S1895 and D21S1921.
I first came across CytoCell FISH probes in a previous lab I worked in and I was struck by the quality of the products. Since this time, I have been recommending and introducing CytoCell probes across all application areas — now they are the primary FISH probes used in our lab. They have an excellent range of products and their ready-to-use reagent format saves considerable time.
Elizabeth Benner
Medical Technologist, University of Arizona Health Network, USA
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