The P16 probe, labeled in red, covers a 193kb region of 9p21.3, including the CDKN2A gene and flanking regions. The probe mix also contains a control probe for chromosome 9 (D9Z3, the heterochromatic block at 9q12) labeled in green.
I first came across CytoCell FISH probes in a previous lab I worked in and I was struck by the quality of the products. Since this time, I have been recommending and introducing CytoCell probes across all application areas — now they are the primary FISH probes used in our lab. They have an excellent range of products and their ready-to-use reagent format saves considerable time.
Elizabeth Benner
Medical Technologist, University of Arizona Health Network, USA
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